Cardiac
GI
Bone
GU
Neuro
Peds
Faculty
Student
Quizzes
Image DDX
Museum
Mobile
  Misc
Videocasts
Signs
Twitter

 

 


Learning
Radiology:
Recognizing
the Basics
Now Available
on the Kindle
and IPad

 

LearningRadiology Imaging Signs
on Twitter

  

Follow us on

Case of the Week 446




What is the most likely diagnosis?

  • 61 year-old being treated for a bone malignancy



3D Reconstruction of CT of the Mandible

  1. Periapical cyst
  2. Fibrous dysplasia
  3. Bisphosphonate-related osteonecrosis
  4. Paget disease
  5. Ovarian metastases

Additional Image - Axial Images of the Mandible

 

Additional Images

 

Axial Images of the Mandible

 


Answer:

 

3. Bisphosphonate-related Osteonecrosis

.

.

More (Click Discussion Tab)


 

Bisphosphonate-Related Osteonecrosis

 

General Considerations

  • Bisphosphonates are commonly prescribed for the treatment and prevention of
    • Osteoporosis (e.g. alendronate, risendronate, ibandronate)
    • Osteolytic lesions in metastatic bone tumors (e.g. breast, prostate, multiple myeloma) (e.g. zoledronate, pamidronate)
    • Hypercalcemia associated with malignancy
  • Bind and inhibit osteoclastic activity
  • There has been an association described between bisphosphonates, usually in higher doses in cancer patients, and avascular necrosis, especially of the mandible

MORE . . .


.

This Week
61 year-old being treated for a bone malignancy
 
Presented as a series of cards, this podcast asks some of the most common causes of neuroimaging findings and diseases making it ideal for a quick review. Can be used as either an audio only or audio/video podcast.; Complements Video Flashcard Podcasts 15, 21,25, 38, 42, 46 and 47.
 
 
Some of the fundamentals of interpreting chest images
 
The top diagnostic imaging diagnoses that all medical students should recognize according to the Alliance of Medical Student Educators in Radiology
 
Recognizing normal and  key abnormal intestinal gas patterns, free air and abdominal calcifications
 
Recognizing the parameters that define a good chest x-ray; avoiding common pitfalls
 
How to recognize the most common arthritides


Now Open!

LearningRadiology
Named Magazine's
"25 Most Influential"

See Article on LearningRadiology
in August, 2010
RSNA News

LearningRadiology.com
is an award-winning educational website aimed primarily at medical students and radiology residents-in-training, containing  lectures, handouts, images, Cases of the Week, archives of cases, quizzes, flashcards of differential diagnoses and “most commons” lists, primarily in the areas of chest, GI, GU cardiac, bone and neuroradiology.